The EUPHORIA partners met on Friday 28 January for an online plenary meeting. The meeting focused on the EUPHORIA study, which is now open at 3 sites (2 in Germany and 1 in Italy), with plans for 2 more sites to open soon (1 in Milan and 1 in Berlin). Recruitment continues despite the challenges presented by COVID-19. As we enter the final 6 months of the project we look forward to the generation of interim study results in the coming weeks. The EUPHORIA team hope to hold our final project meeting in person in May/June 2022.